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Blood transfusion department of our hospital successfully matched the blood of a rare antibody patient
Author:xaszxyy  Release date:2018-09-03


    On the night of May 29, an elderly patient in the digestive department of Central Hospital with cirrhosis was finally given a long-awaited red blood cell suspension. The process of blood transfusion lasted two days, which was the first non-homogenous blood transfusion in our hospital.Blood was not in short supply these days, and the patient had already haven multiple blood transfusions. This time, why is her transfusion so difficult?

    Severe anemia, urgent need for blood transfusion, but the patient's own agglutination and irregular antibody screening I cells were positive. The results of one experiment after another proved that the conventional blind matching was useless. At last, The patient was identified as type O RH factor CCDee with the assistance of blood type room in blood station. He produced very rare class C antibodies by uncertain factors such as multiple transfusions or drugs, which the probability of being present in the people was extremely low. Besides, with the patient’s own agglutination, we could only injected RH factors of ccDee and ccdee, as well as erythrocyte suspension which the agglutination intensity was weaker than that of self agglutination. ccDee was rarely distributed in the population. After discussion of blood transfusion department director Yangmin Zhang and astroenterology department director Kun Zhuang, they suggested that Type O washes red blood cells which the RH factor was ccdee should be injected. According to the cross blood test of the three mediators, they matched the patient with a sufficient number of ccdee's O - type RH negative erythrocytes. The transfusion process was successful. The patient's anemia improved quickly.

    It is our incumbent duty to provide matching blood for every patient who really needs blood transfusion, including difficult and rare blood types. These difficult cases of blood use have prompted us to master new technologies, accept new tests, try new ways and make new progress.